Rejuran Treatment in Pune – Regenerate Your Skin Naturally

Beautiful skin isn’t just about looking younger—it’s about having healthy, resilient skin from within. If you’re looking for a treatment that improves skin quality rather than simply adding volume, Rejuran Treatment is one of the most advanced regenerative aesthetic procedures available today.
Originally developed in South Korea, Rejuran has become a popular choice worldwide for patients seeking natural skin rejuvenation, collagen stimulation, and improved skin texture. Unlike fillers that primarily restore lost volume, Rejuran focuses on repairing damaged skin at the cellular level using purified polynucleotides (PNs) derived from salmon DNA, which are highly biocompatible with human tissue. Current evidence suggests polynucleotide treatments may improve skin texture, elasticity, hydration, and fine wrinkles, although more high-quality studies are still needed to define their optimal use.
At Aesthetic World Clinic, we provide customised Rejuran treatment plans designed to restore healthier, firmer, and naturally radiant skin.
What is Rejuran Treatment?
Rejuran is an injectable polynucleotide (PN) skin regenerative treatment that stimulates your skin’s natural healing process.
The purified DNA fragments help:
- Stimulate collagen production
- Repair damaged skin cells
- Improve skin elasticity
- Enhance skin hydration
- Reduce inflammation
- Strengthen the skin barrier
Rather than changing your facial shape, Rejuran improves the quality of your skin, making it healthier and more youthful over time. Clinical studies have reported improvements in wrinkle appearance and skin quality with an acceptable safety profile, though outcomes vary between individuals.
How Does Rejuran Work?
As we age, collagen production slows down.
Skin becomes:
- Thin
- Dry
- Less elastic
- Rough
- Wrinkled
Rejuran works by encouraging fibroblasts (collagen-producing cells) to repair damaged tissue.
This process helps:
✔ Increase collagen
✔ Improve elastin
✔ Repair damaged skin
✔ Improve microcirculation
✔ Enhance tissue regeneration
Instead of masking ageing, Rejuran supports your skin’s own regenerative processes.
Benefits of Rejuran Treatment
1. Skin Rejuvenation
Improves overall skin health and texture.
2. Fine Line Reduction
Softens:
- Crow’s feet
- Smile lines
- Fine wrinkles
- Neck lines
3. Acne Scar Improvement
Helps remodel superficial acne scars by improving collagen formation. It is often combined with procedures such as microneedling, RF microneedling, or fractional lasers for enhanced results.
4. Smaller Pores
Strengthens skin structure and improves pore appearance.
5. Better Skin Hydration
Provides healthier, plumper skin.
6. Under Eye Rejuvenation
Useful for:
- Crepey skin
- Fine wrinkles
- Mild dark circles
- Thin under-eye skin
7. Improved Skin Elasticity
Skin feels firmer and smoother.
8. Healthier Skin Barrier
Supports recovery from environmental damage and ageing.
Who is an Ideal Candidate?
Rejuran is suitable for adults who want to improve skin quality rather than facial volume.
You may benefit if you have:
- Fine wrinkles
- Enlarged pores
- Acne scars
- Dull skin
- Sun-damaged skin
- Uneven texture
- Thin under-eye skin
- Mild skin laxity
- Early signs of ageing
Areas That Can Be Treated
Rejuran can be used for:
- Face
- Neck
- Under eyes
- Forehead
- Cheeks
- Jawline
- Hands
- Décolletage
Conditions Treated
Rejuran may help improve the appearance of:
- Acne scars
- Enlarged pores
- Fine wrinkles
- Photoaged skin
- Uneven texture
- Dehydrated skin
- Mild pigmentation (as part of a broader treatment plan)
- Crepey skin
- Under-eye ageing
The Rejuran Procedure
Consultation
Your skin is analysed to determine suitability and whether Rejuran alone or in combination with other treatments is appropriate.
Skin Preparation
The face is cleansed thoroughly.
Numbing Cream
A topical anaesthetic is usually applied for comfort.
Micro Injections
Rejuran is injected into targeted areas using fine needles or an injector device.
Cooling
Cooling and soothing products are applied after treatment.
The entire procedure usually takes 30–45 minutes.
Is Rejuran Treatment Painful?
Most patients describe mild discomfort.
Topical anaesthetic significantly improves comfort during treatment.
Temporary injection bumps usually settle within 24–72 hours.
Downtime
Recovery is generally minimal.
Possible temporary effects include:
- Mild redness
- Small bumps
- Swelling
- Tenderness
- Occasional bruising
These effects usually resolve within a few days.
When Will I See Results?
Most patients notice:
1–2 Weeks
- Improved hydration
- Better glow
3–4 Weeks
- Better texture
- Reduced pores
2–3 Months
- Increased firmness
- Softer fine lines
- Improved skin quality
Collagen remodelling continues gradually over time.
How Many Sessions Are Needed?
Most treatment plans involve:
- 3 sessions
- 3–4 weeks apart
Maintenance may be recommended every 6–12 months, depending on skin concerns and response.
Rejuran treatment(polynucleiotide) vs Dermal Fillers
| Rejuran | Dermal Fillers |
|---|---|
| Improves skin quality | Adds facial volume |
| Stimulates collagen | Immediate contouring |
| Natural skin regeneration | Corrects volume loss |
| Improves texture | Improves facial shape |
| Best for skin ageing | Best for structural enhancement |
Rejuran vs Profhilo
| Rejuran | Profhilo |
|---|---|
| Polynucleotides | Hyaluronic acid |
| Repairs damaged skin | Bio-remodelling and hydration |
| Excellent for acne scars | Excellent for skin laxity |
| Improves skin texture | Improves hydration and firmness |
Rejuran vs PRP
| Rejuran | PRP |
|---|---|
| Standardised injectable product | Uses the patient’s own blood |
| No blood draw required | Requires blood collection |
| Focus on skin regeneration | Growth factor-based regeneration |
| Consistent formulation | Results may vary with individual factors |
Aftercare Tips
For the first 24–48 hours:
- Avoid heavy exercise
- Avoid sauna and steam
- Avoid alcohol if advised by your clinician
- Do not massage treated areas unless instructed
- Avoid harsh exfoliants
- Use sunscreen daily
- Keep skin well moisturised
Safety
Rejuran has been used widely in aesthetic practice and is generally well tolerated when performed by trained professionals. Common side effects are mild and temporary, such as redness, swelling, bruising, or small injection bumps. As with any injectable procedure, there is a small risk of infection, allergic reaction, or vascular complications, making proper patient selection and technique essential.
Why Choose Aesthetic World Clinic?
At Aesthetic World Clinic, every patient receives an individualised treatment plan based on skin type, concerns, and aesthetic goals.
Our approach includes:
- Comprehensive skin assessment
- Personalised treatment protocols
- Advanced injection techniques
- Strict infection control
- Combination therapies where appropriate
- Detailed aftercare guidance
- Focus on natural-looking results
Frequently Asked Questions (FAQs)
Is Rejuran safe?
Yes. When administered by a qualified medical professional after appropriate assessment, Rejuran has demonstrated a favourable safety profile.
How long do results last?
Results commonly last 6–12 months, depending on age, skin condition, lifestyle, and maintenance.
Can Rejuran remove acne scars?
It can improve the appearance of many acne scars, particularly when combined with treatments such as microneedling or fractional laser.
Is there downtime?
Most patients return to normal activities within one to three days.
Can Rejuran be combined with other treatments?
Yes. It is frequently combined with:
- Microneedling
- RF Microneedling
- Fractional CO₂ Laser
- Pico Laser
- Chemical Peels
- PRP
- Exosome therapy
The most suitable combination depends on your skin concerns.
Is Rejuran suitable for all skin types?
It is generally suitable for many skin types, but a consultation is necessary to assess suitability and rule out contraindications.
Is Rejuran a filler?
No. Rejuran is a regenerative skin treatment and does not primarily add facial volume.
When can I wear makeup?
Most clinicians advise waiting until the next day or at least 24 hours after treatment, depending on your skin’s recovery.
How often should maintenance be done?
Typically every 6–12 months, although this varies between individuals.
Does Rejuran permanently stop ageing?
No. It improves skin quality and may slow visible signs of ageing, but the natural ageing process continues.
Book Your Rejuran Consultation at Aesthetic World Clinic
If you’re looking for a treatment that enhances your skin’s health, texture, hydration, and radiance while encouraging natural collagen production, Rejuran may be an excellent option.
A personalised consultation at Aesthetic World Clinic can help determine whether Rejuran is the right choice for your skin goals and whether combination treatments may offer additional benefits.